Orthopedic, Prosthetic & Surgical Appliances & Supplies · SIC 3842

MILESTONE SCIENTIFIC INC.

MLSS

Watch

Latest revenue

$2.2M

as of 2026-03-31

Latest net income

$-839.9K

as of 2026-03-31

Net margin

-38.8%

as of 2026-03-31

Price · 5Y

-28.8% / yr 42.6 pts / yr vs S&P 500 81.6% total
Compare:

Live market

delayed ≤15 min
$0.38
1.77%
Market cap
$33.7M
Enterprise value
$33.7M
P/E (trailing)
Forward P/E
P/B
Dividend yield
0.0%
52-wk high
$1.01
52-wk low
$0.22
Beta
Shares out
88.1M

5-year trend

What this company does

AI

Item 1. Business Overview Milestone Scientific Inc. was incorporated in the State of Delaware in August 1989. The Company develops and commercializes proprietary computer-controlled drug delivery systems designed to enhance the safety, precision, and patient experience associated with subcutaneous injections and fluid aspiration procedures. The Company’s core technology platform, Dynamic Pressure Sensing® (“DPS”) Technology, controls flow rate and measures pressure at the needle tip in real time. DPS Technology is incorporated into both the Company’s dental and medical products and supports clinical applications, including local anesthesia delivery, epidural space identification in regional…

AI summary unavailable — showing raw filing excerpt

Generated from MLSS's filing dated 2026-03-31

Key risks

AI

Item 1A. Risk Factors You should carefully consider the risks and uncertainties described below, together with the other information included in this Annual Report on Form 10-K. If any of the risks described below occur, our business, financial condition, results of operations, and prospects could be materially and adversely affected. The risks described below are not the only risks we face. Additional risks and uncertainties that we do not currently know about, or that we currently believe are immaterial, also may materially and adversely affect our business, financial condition, results of operations, and/or prospects. These disclosures reflect the Company’s beliefs and opinions as to…

AI summary unavailable — showing raw filing excerpt

Generated from MLSS's filing dated 2026-03-31

Profitability

Gross margin

71.4%

4.2%

Operating margin

-63.5%

18.9%

Net margin

-63.8%

16.7%

Return on equity

-203.4%

151.8%

Return on assets

-73.3%

52.4%

Leverage

Debt / equity

1.78×

161.2%

Long-term debt / equity

0.28×

2934.5%

Debt / assets

64.0%

58.1%

Earnings tracker

QuarterRevenueYoYNet incomeYoYNet margin

Q1 2026

2026-03-31

$2.2M-3.2%$-839.9K+57.9%-38.8%

Q4 2025

2025-12-31

$2.1M+2.2%

Q3 2025

2025-09-30

$2.4M-6.1%$-1.2M+21.0%-48.9%

Q2 2025

2025-06-30

$2.3M+25.3%

Q1 2025

2025-03-31

$2.2M-0.7%$-2.0M-38.5%-89.3%

Q4 2024

2024-12-31

$2.0M$-2.0M-101.1%

Q3 2024

2024-09-30

$2.5M+22.1%$-1.5M+0.3%-58.1%

Q2 2024

2024-06-30

$1.9M-36.3%$223.6K+110.1%12.1%

Year-over-year change vs the same fiscal quarter one year prior. Revenue + net income sourced from SEC 10-Q / 10-K filings — no analyst-consensus dependency.

Industry trend

Orthopedic, Prosthetic & Surgical Appliances & Supplies · SIC 3842

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Insider activity

Insider buying

$0

Insider selling

$471.7K

Net activity

−$471.7K

Distinct insiders

1

Open-market trades over the last 365 days.

Recent transactions

DateInsiderTypeSharesPriceValue
2025-10-24

BP4 S.r.l.

10%+ owner

Sale100,000$0.44$44.0K
2025-10-23

BP4 S.r.l.

10%+ owner

Sale80,000$0.43$34.4K
2025-10-22

BP4 S.r.l.

10%+ owner

Sale14,427$0.45$6.5K
2025-10-21

BP4 S.r.l.

10%+ owner

Sale40,000$0.44$17.6K
2025-10-20

BP4 S.r.l.

10%+ owner

Sale24,034$0.45$10.9K
2025-10-14

BP4 S.r.l.

10%+ owner

Sale30,000$0.54$16.2K
2025-10-13

BP4 S.r.l.

10%+ owner

Sale10,000$0.55$5.5K
2025-10-10

BP4 S.r.l.

10%+ owner

Sale10,158$0.55$5.6K
2025-10-08

BP4 S.r.l.

10%+ owner

Sale30,000$0.47$13.9K
2025-10-07

BP4 S.r.l.

10%+ owner

Sale10,000$0.45$4.5K
2025-10-03

BP4 S.r.l.

10%+ owner

Sale9,210$0.45$4.1K
2025-10-03

BP4 S.r.l.

10%+ owner

Sale10,000$0.45$4.5K
2025-09-11

BP4 S.r.l.

10%+ owner

Sale10,000$0.59$5.9K
2025-07-17

BP4 S.r.l.

10%+ owner

Sale10,000$0.64$6.4K
2025-07-08

BP4 S.r.l.

10%+ owner

Sale11,489$0.69$7.9K
2025-07-07

BP4 S.r.l.

10%+ owner

Sale30,558$0.68$20.8K
2025-07-03

BP4 S.r.l.

10%+ owner

Sale50,853$0.67$34.1K
2025-06-30

BP4 S.r.l.

10%+ owner

Sale649$0.65$422
2025-06-27

BP4 S.r.l.

10%+ owner

Sale10,000$0.73$7.3K
2025-06-25

BP4 S.r.l.

10%+ owner

Sale1,300$0.77$1.0K
2025-06-24

BP4 S.r.l.

10%+ owner

Sale10,000$0.81$8.1K
2025-06-23

BP4 S.r.l.

10%+ owner

Sale5,933$0.86$5.1K
2025-06-18

BP4 S.r.l.

10%+ owner

Sale1,693$0.88$1.5K
2025-06-16

BP4 S.r.l.

10%+ owner

Sale10,056$0.90$9.0K
2025-06-11

BP4 S.r.l.

10%+ owner

Sale23,797$0.90$21.5K
2025-06-10

BP4 S.r.l.

10%+ owner

Sale30,100$0.91$27.4K
2025-06-09

BP4 S.r.l.

10%+ owner

Sale20,266$0.91$18.3K
2025-06-06

BP4 S.r.l.

10%+ owner

Sale60,200$0.90$54.3K
2025-06-05

BP4 S.r.l.

10%+ owner

Sale26,855$0.91$24.4K
2025-06-04

BP4 S.r.l.

10%+ owner

Sale6,000$0.91$5.5K

Source: SEC Form 4 filings. Officers, directors, and 10%+ owners must disclose share transactions within two business days. RSU grants and tax-withholding rows are excluded by default — compensation activity is not a trading signal.

Who owns MLSS

Institutional value

$918.5K

Total shares held

3.2M

Distinct holders

21

-10 vs prior

As of

2026-03-31

Prior: 2025-12-31

Filers with $100M+ AUM disclose holdings 45 days after quarter end.

Top institutional holders

#ManagerSharesValueQoQ changeAction
1VANGUARD CAPITAL MANAGEMENT LLC2.0M$572.2KNew
2VANGUARD FIDUCIARY TRUST CO321.6K$92.6KNew
3LPL Financial LLC124.9K$36.0K+20.0K (+19.1%)Added
4Mariner, LLC121.8K$35.1K+0 (+0.0%)No change
5World Investment Advisors104.0K$30.0K-96.0K (-48.0%)Trimmed
6Carnegie Investment Counsel100.2K$28.9K+0 (+0.0%)No change
7BlackRock, Inc.65.5K$18.9K-5.4K (-7.6%)Trimmed
8UBS Group AG62.5K$18.0K-33.4K (-34.8%)Trimmed
9Brookwood Investment Group LLC49.1K$14.1K+0 (+0.0%)No change
10COMMONWEALTH EQUITY SERVICES, LLC44.8K$12.9KNew
11Sequoia Financial Advisors, LLC43.4K$12.5K+0 (+0.0%)No change
12Kestra Advisory Services, LLC41.1K$11.8K+0 (+0.0%)No change
13Newbridge Financial Services Group, Inc.41.0K$11.8K+37.0K (+925.0%)Added
14Cetera Investment Advisers17.1K$4.9K+0 (+0.0%)No change
15HighTower Advisors, LLC15.7K$4.5K+0 (+0.0%)No change
16Radnor Capital Management, LLC15.0K$4.3K+0 (+0.0%)No change
17Vanguard Global Advisers, LLC14.9K$4.3KNew
18OPPENHEIMER & CO INC10.0K$2.9K+0 (+0.0%)No change
19DOCK STREET ASSET MANAGEMENT INC10.0K$2.9K+0 (+0.0%)No change
20JPMORGAN CHASE & CO220$67+0 (+0.0%)No change

Source: SEC Form 13F-HR. Positions aggregated across sub-managers within each firm. Options (puts/calls) excluded — common stock only.

Top questions investors are asking

Coming once MLSS's latest filing finishes processing.