Biological Products, (No Diagnostic Substances) · SIC 2836

BIOCRYST PHARMACEUTICALS INC

BCRX

Watch

Latest revenue

$156.4M

as of 2026-03-31

Latest net income

$-721.8M

as of 2026-03-31

Net margin

-461.5%

as of 2026-03-31

Price · 5Y

-12.1% / yr 25.9 pts / yr vs S&P 500 47.4% total
Compare:

Live market

delayed ≤15 min
$8.29
0.96%
Market cap
$2.11B
Enterprise value
$2.11B
P/E (trailing)
8.0×
Forward P/E
P/B
Dividend yield
0.0%
52-wk high
$11.31
52-wk low
$6.00
Beta
Shares out
254.2M

5-year trend

What this company does

AI

ITEM 1. BUSINESS Our Business We are a global biotechnology company focused on developing and commercializing medicines for hereditary angioedema (“HAE”) and other rare diseases, driven by our deep commitment to improving the lives of people living with these conditions. We have built a robust commercial infrastructure to support the successful commercialization of ORLADEYO, an oral, once-daily therapy discovered and developed internally for the prevention of HAE attacks. Our business strategy includes leveraging this established commercial platform to successfully commercialize a pipeline of potential first-in-class or best-in class oral small molecule and injectable protein therapeutics…

AI summary unavailable — showing raw filing excerpt

Generated from BCRX's filing dated 2026-02-26

Key risks

AI

Table of Contents ITEM 1A. RISK FACTORS An investment in our stock involves risks. You should carefully read this entire report and consider the following uncertainties and risks, which may adversely affect our business, financial condition or results of operations, along with all of the other information included in our other filings with the SEC, before making an investment decision regarding our common stock. Additionally, while some of the factors, events and contingencies described herein may have occurred in the past, the disclosures herein are not representations as to whether or not they have occurred and are instead provided because future occurrences thereof could adversely affect…

AI summary unavailable — showing raw filing excerpt

Generated from BCRX's filing dated 2026-02-26

Profitability

Operating margin

39.0%

7008.2%

Net margin

30.2%

252.9%

Return on equity

-221.4%

1285.8%

Return on assets

51.3%

383.2%

Leverage

Debt / equity

-5.32×

161.8%

Long-term debt / equity

-0.01×

98.2%

Debt / assets

123.2%

37.5%

Earnings tracker

QuarterRevenueYoYNet incomeYoYNet margin

Q1 2026

2026-03-31

$156.4M+7.5%$-721.8M-2255762.5%-461.5%

Q4 2025

2025-12-31

$406.6M+209.1%$245.8M+1017.5%60.5%

Q3 2025

2025-09-30

$159.4M+36.1%$12.9M+191.9%8.1%

Q2 2025

2025-06-30

$163.4M+49.4%$5.1M+140.1%3.1%

Q1 2025

2025-03-31

$145.5M+56.9%$32.0K+100.1%0.0%

Q4 2024

2024-12-31

$131.5M$-26.8M-20.4%

Q3 2024

2024-09-30

$117.1M+35.0%$-14.0M+61.2%-12.0%

Q2 2024

2024-06-30

$109.3M+32.5%$-12.7M+83.2%-11.6%

Year-over-year change vs the same fiscal quarter one year prior. Revenue + net income sourced from SEC 10-Q / 10-K filings — no analyst-consensus dependency.

Industry trend

Biological Products, (No Diagnostic Substances) · SIC 2836

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Insider activity

Insider buying

$0

Insider selling

$4.7M

Net activity

−$4.7M

Distinct insiders

4

Open-market trades over the last 365 days.

Recent transactions

DateInsiderTypeSharesPriceValue
2026-05-18

Amy E Mckee

Director

Sale11,180$8.97$100.3K
2026-05-13

Alane P Barnes

Chief Legal Officer

Sale62,500$9.54$596.3K
2026-03-20

Theresa Heggie

Director

Sale49,933$10.11$504.8K
2026-03-16

Alane P Barnes

Chief Legal Officer

Sale150,000$9.15$1.4M
2025-12-22

Alane P Barnes

Chief Legal Officer

Sale21,773$7.65$166.6K
2025-12-15

Alane P Barnes

Chief Legal Officer

Sale21,210$7.65$162.3K
2025-12-03

Alane P Barnes

Chief Legal Officer

Sale19,770$7.65$151.2K
2025-12-02

Alane P Barnes

Chief Legal Officer

Sale50,906$7.21$367.2K
2025-12-01

Alane P Barnes

Chief Legal Officer

Sale91,004$7.10$646.5K

Source: SEC Form 4 filings. Officers, directors, and 10%+ owners must disclose share transactions within two business days. RSU grants and tax-withholding rows are excluded by default — compensation activity is not a trading signal.

Who owns BCRX

Institutional value

$911.5M

Total shares held

99.3M

Distinct holders

166

-105 vs prior

As of

2026-03-31

Prior: 2025-12-31

Filers with $100M+ AUM disclose holdings 45 days after quarter end.

Top institutional holders

#ManagerSharesValueQoQ changeAction
1BlackRock, Inc.22.7M$215.6M+1.5M (+7.2%)Added
2VANGUARD PORTFOLIO MANAGEMENT LLC11.2M$107.0MNew
3VANGUARD CAPITAL MANAGEMENT LLC11.1M$106.0MNew
4abrdn plc5.0M$48.0M+4.1M (+451.7%)Added
5UBS Group AG4.9M$47.1M-319.9K (-6.1%)Trimmed
6Nuveen, LLC3.8M$36.4M+206.9K (+5.7%)Added
7RFG Advisory, LLC2.9M$27.3MNew
8Fisher Asset Management, LLC2.7M$26.0M+265.7K (+10.8%)Added
9OP Asset Management Ltd2.5M$25.7M+2.4M (+1700.0%)Added
10DIMENSIONAL FUND ADVISORS LP2.7M$25.6M+1.5M (+119.0%)Added
11Candriam S.C.A.2.3M$21.8MNew
12STIFEL FINANCIAL CORP1.8M$17.4M+667 (+0.0%)Added
13VANGUARD FIDUCIARY TRUST CO1.7M$15.8MNew
14JPMORGAN CHASE & CO1.5M$14.6M+698.6K (+82.8%)Added
15Legal & General Group Plc1.4M$13.4M+1.2M (+568.8%)Added
16Invesco Ltd.1.3M$12.5M-46.1K (-3.4%)Trimmed
17BNP PARIBAS FINANCIAL MARKETS1.3M$12.4M-1.2M (-48.8%)Trimmed
18JUPITER ASSET MANAGEMENT LTD1.2M$11.4M-1.2K (-0.1%)Trimmed
19DEUTSCHE BANK AG\821.4K$7.8M+330.3K (+67.3%)Added
20FIRST TRUST ADVISORS LP800.9K$7.6M+425.9K (+113.6%)Added

Source: SEC Form 13F-HR. Positions aggregated across sub-managers within each firm. Options (puts/calls) excluded — common stock only.

Top questions investors are asking

Coming once BCRX's latest filing finishes processing.