Biological Products, (No Diagnostic Substances) · SIC 2836

Aura Biosciences, Inc.

AURA

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Latest revenue

as of 2025-12-31

Latest net income

$-106.2M

as of 2025-12-31

Net margin

as of 2025-12-31

5.3
of 10

ActaClear Score

Neutral
#131 of 165 in Biological Products, (No Diagnostic Substances)
new
Profitability·25%
5.1
Growth·15%
Value·20%
4.7
Quality·20%
Momentum·20%
6.3

Computed from 5 years of SEC fundamentals + latest market data, ranked within Biological Products, (No Diagnostic Substances) (165 peers). 10 = best in industry, 5 = median, 0 = worst. Refreshed Jun 6, 2026.

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Price · 5Y

-19.2% / yr 38.9 pts / yr vs S&P 500 62.1% total
Compare:

Market data

Price feed temporarily unavailable for AURA.

5-year trend

What this company does

AI

Item 1. Business. Overview We are a clinical-stage biotechnology company developing precision therapies to treat solid tumors designed to preserve organ function. Our lead candidate bel-sar is in late-stage clinical development for the treatment of patients with early choroidal melanoma (defined as small choroidal melanoma and/or indeterminate lesions) and is also in clinical development for other ocular oncology indications and bladder cancer. There is significant unmet need for novel treatments for patients with choroidal melanoma, given the limitations of the current standard of care, or SoC, and patient reluctance to undergo radiotherapy in the form of either plaque brachytherapy or…

AI summary unavailable — showing raw filing excerpt

Generated from AURA's filing dated 2026-03-30

Key risks

AI

Item 1A. Risk Factors. Investing in our common stock involves a high degree of risk. You should carefully read and consider all of the risks described below, as well as the other information in this Annual Report on Form 10-K, including our consolidated financial statements and related notes thereto and the section titled “Management’s Discussion and Analysis of Financial Condition and Results of Operations”. The occurrence of any of the events or developments described below could harm our business, financial condition, results of operations and growth prospects. Unless otherwise indicated, references to our business being harmed in these risk factors will include harm to our business,…

AI summary unavailable — showing raw filing excerpt

Generated from AURA's filing dated 2026-03-30

Profitability

Return on equity

-77.6%

35.6%

Return on assets

-62.7%

31.6%

Leverage

Debt / equity

0.24×

18.2%

Debt / assets

19.2%

14.7%

Earnings tracker

QuarterRevenueYoYNet incomeYoYNet margin

Q1 2026

2026-03-31

$-33.7M-22.6%

Q4 2025

2025-12-31

$-25.6M+1.1%

Q3 2025

2025-09-30

$-26.1M-24.2%

Q2 2025

2025-06-30

$-27.0M-32.9%

Q1 2025

2025-03-31

$-27.5M-39.5%

Q4 2024

2024-12-31

$-25.8M

Q3 2024

2024-09-30

$-21.0M-13.7%

Q2 2024

2024-06-30

$-20.3M-11.1%

Year-over-year change vs the same fiscal quarter one year prior. Revenue + net income sourced from SEC 10-Q / 10-K filings — no analyst-consensus dependency.

Industry trend

Biological Products, (No Diagnostic Substances) · SIC 2836

No data yet for industry average

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Insider activity

Insider buying

$0

Insider selling

$40.0M

Net activity

−$40.0M

Distinct insiders

6

Open-market trades over the last 365 days.

Recent transactions

DateInsiderTypeSharesPriceValue
2026-05-07

Matrix Capital Management Company, LP / David E. Goel

10%+ owner

Sale6,922,870$5.64$39.0M
2026-04-16

Conor Kilroy

Chief Legal Officer and Secretary.

Sale11,738$7.02$82.4K
2026-02-17

Conor Kilroy

Chief Legal Officer and Secretary.

Sale12,079$5.05$61.0K
2026-02-17

Mark Plavsic

Chief Technology Officer

Sale15,890$5.05$80.2K
2026-02-17

Janet Jill Hopkins

Chief Medical Officer

Sale20,401$5.06$103.2K
2026-02-17

Amy Elazzouzi

Senior Vice President, Finance

Sale8,549$5.06$43.3K
2026-02-17

Pinos Elisabet De Los

President and Chief Executive Officer

Sale47,648$5.06$241.1K
2026-01-20

Amy Elazzouzi

Senior Vice President, Finance

Sale1,581$4.86$7.7K
2026-01-20

Pinos Elisabet De Los

President and Chief Executive Officer

Sale16,928$4.86$82.3K
2025-11-17

Janet Jill Hopkins

Chief Medical Officer

Sale17,109$5.42$92.7K
2025-10-29

Amy Elazzouzi

Senior Vice President, Finance

Sale896$6.35$5.7K
2025-10-29

Pinos Elisabet De Los

President and Chief Executive Officer

Sale9,049$6.35$57.5K
2025-10-16

Mark Plavsic

Chief Technology Officer

Sale12,169$6.35$77.3K
2025-08-18

Amy Elazzouzi

Senior Vice President, Finance

Sale7,722$6.70$51.7K

Source: SEC Form 4 filings. Officers, directors, and 10%+ owners must disclose share transactions within two business days. RSU grants and tax-withholding rows are excluded by default — compensation activity is not a trading signal.

Who owns AURA

Institutional value

$99.0M

Total shares held

14.8M

Distinct holders

62

-55 vs prior

As of

2026-03-31

Prior: 2025-12-31

Filers with $100M+ AUM disclose holdings 45 days after quarter end.

Top institutional holders

#ManagerSharesValueQoQ changeAction
1BlackRock, Inc.3.6M$24.0M+26.2K (+0.7%)Added
2Medicxi Ventures Management (Jersey) Ltd3.0M$20.3M+0 (+0.0%)No change
3VANGUARD CAPITAL MANAGEMENT LLC2.2M$15.0MNew
4FRANKLIN RESOURCES INC2.1M$13.9M-125.7K (-5.7%)Trimmed
5LEVIN CAPITAL STRATEGIES, L.P.941.4K$6.3M-94.2K (-9.1%)Trimmed
6DIMENSIONAL FUND ADVISORS LP558.2K$3.7M+40.2K (+7.8%)Added
7Regency Capital Management Inc.\DE532.5K$3.6M-6.1K (-1.1%)Trimmed
8VANGUARD FIDUCIARY TRUST CO397.2K$2.7MNew
9VANGUARD PORTFOLIO MANAGEMENT LLC391.3K$2.6MNew
10UBS Group AG118.9K$795.5K-52.7K (-30.7%)Trimmed
11Bank of New York Mellon Corp99.4K$665.2K-8.5K (-7.9%)Trimmed
12BNP PARIBAS FINANCIAL MARKETS90.1K$602.5K-24.6K (-21.4%)Trimmed
13Fisher Asset Management, LLC83.5K$558.7KNew
14Nuveen, LLC72.7K$486.4K+378 (+0.5%)Added
15RHUMBLINE ADVISERS64.7K$433.0K-314 (-0.5%)Trimmed
16TBH Global Asset Management, LLC60.3K$403.6K+0 (+0.0%)No change
17TD ASSET MANAGEMENT INC40.5K$271.0K+0 (+0.0%)No change
18Vanguard Global Advisers, LLC39.8K$266.2KNew
19DEUTSCHE BANK AG\38.0K$254.0K+7.1K (+23.2%)Added
20Invesco Ltd.34.3K$229.3K+7.0K (+25.6%)Added

Source: SEC Form 13F-HR. Positions aggregated across sub-managers within each firm. Options (puts/calls) excluded — common stock only.

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