Biological Products, (No Diagnostic Substances) · SIC 2836

Alector, Inc.

ALEC

Watch

Latest revenue

$1.0M

as of 2026-03-31

Latest net income

$-22.9M

as of 2026-03-31

Net margin

-2192.2%

as of 2026-03-31

5.7
of 10

ActaClear Score

Neutral
#106 of 165 in Biological Products, (No Diagnostic Substances)
+0.0 · 2d
Profitability·25%
5.0
Growth·15%
6.5
Value·20%
4.2
Quality·20%
8.2
Momentum·20%
5.0

Computed from 5 years of SEC fundamentals + latest market data, ranked within Biological Products, (No Diagnostic Substances) (165 peers). 10 = best in industry, 5 = median, 0 = worst. Refreshed Jun 7, 2026.

Community sentiment

Where do you think ALEC is heading?

1 month
6 months
12 months
5 years
Sign in free to vote and see community sentiment

Price · 5Y

-39.3% / yr 59.0 pts / yr vs S&P 500 91.7% total
Compare:

Live market

delayed ≤15 min
$1.63
Market cap
$181.0M
Enterprise value
$113.8M
P/E (trailing)
Forward P/E
P/B
17.43×
Dividend yield
0.0%
52-wk high
$3.40
52-wk low
$1.09
Beta
Shares out
111.0M

5-year trend

What this company does

AI

Item 1. Business. Overview We are a clinical-stage biotechnology company developing therapies for neurodegenerative diseases, with a focus on areas of high unmet medical need. Our work is informed by advances in disease biology, including the roles of misfolded or deficient proteins, lysosomal dysfunction, and immune and neuronal pathway disruption. Our objective is to develop product candidates that address disease through targeted mechanisms, such as removing pathogenic proteins, replacing deficient proteins, and restoring normal cellular function. We are advancing a portfolio of programs focused on genetically validated targets, supported by our expertise in drug development, protein…

AI summary unavailable — showing raw filing excerpt

Generated from ALEC's filing dated 2026-02-25

Key risks

AI

Item 1A. Risk Factors. Investing in our common stock involves a high degree of risk. You should carefully consider the risks described below, as well as the other information in this Annual Report on Form 10-K, including our financial statements and the related notes and the section titled “Management’s Discussion and Analysis of Financial Condition and Results of Operations,” and in our other public filings, in evaluating our business. The occurrence of any of the events or developments described below could harm our business, financial condition, results of operations, and growth prospects. In such an event, the market price of our common stock could decline, and you may lose all or part…

AI summary unavailable — showing raw filing excerpt

Generated from ALEC's filing dated 2026-02-25

Profitability

Operating margin

-741.3%

414.1%

Net margin

-679.2%

473.7%

Return on equity

-466.3%

396.7%

Return on assets

-48.7%

91.7%

Leverage

Debt / equity

8.57×

218.1%

Long-term debt / equity

0.30×

310.8%

Debt / assets

89.5%

22.8%

Earnings tracker

QuarterRevenueYoYNet incomeYoYNet margin

Q1 2026

2026-03-31

$1.0M-71.5%$-22.9M+43.3%-2192.2%

Q4 2025

2025-12-31

$6.2M-88.5%$-37.3M-1696.9%-597.5%

Q3 2025

2025-09-30

$3.3M-78.8%$-34.7M+17.9%-1063.4%

Q2 2025

2025-06-30

$7.9M-47.8%$-30.5M+21.1%-387.7%

Q1 2025

2025-03-31

$3.7M-76.9%$-40.5M-12.2%-1101.6%

Q4 2024

2024-12-31

$54.2M$-2.1M-3.8%

Q3 2024

2024-09-30

$15.3M+68.4%$-42.2M+5.1%-275.2%

Q2 2024

2024-06-30

$15.1M-73.2%$-38.7M-2912.8%-256.4%

Year-over-year change vs the same fiscal quarter one year prior. Revenue + net income sourced from SEC 10-Q / 10-K filings — no analyst-consensus dependency.

Industry trend

Biological Products, (No Diagnostic Substances) · SIC 2836

Your notes

Keep private notes on ALEC — thesis, target price, catalysts to watch.

Visible only to you. Never shared. Never used to train AI.

Sign in to write a note

Insider activity

Insider buying

$0

Insider selling

$775.1K

Net activity

−$775.1K

Distinct insiders

6

Open-market trades over the last 365 days.

Recent transactions

DateInsiderTypeSharesPriceValue
2026-04-16

Grace Wong-Sarad

Principal Accounting Officer

Sale1,820$2.65$4.8K
2026-03-10

Grace Wong-Sarad

Principal Accounting Officer

Sale1,000$2.65$2.6K
2026-03-03

Grace Wong-Sarad

Principal Accounting Officer

Sale3,367$2.08$7.0K
2026-03-02

Grace Wong-Sarad

Principal Accounting Officer

Sale8,071$2.12$17.1K
2026-03-02

Arnon Rosenthal

Chief Executive Officer

Sale81,864$2.12$173.8K
2026-03-02

Neil Lindsay Berkley

CFO & Chief Business Officer

Sale29,649$2.12$63.0K
2026-02-26

Grace Wong-Sarad

Principal Accounting Officer

Sale4,079$2.50$10.2K
2025-12-05

Grace Wong-Sarad

Principal Accounting Officer

Sale4,753$1.21$5.8K
2025-12-03

Grace Wong-Sarad

Principal Accounting Officer

Sale8,056$1.12$9.0K
2025-12-03

Arnon Rosenthal

Chief Executive Officer

Sale104,347$1.12$116.8K
2025-12-03

Sara Kenkare-Mitra

President and Head of R&D

Sale41,687$1.12$46.7K
2025-12-03

Neil Lindsay Berkley

Chief Bus Ofcr & Interim CFO

Sale37,261$1.12$41.7K
2025-09-02

Grace Wong-Sarad

Principal Accounting Officer

Sale5,910$2.50$14.8K
2025-09-02

Neil Lindsay Berkley

Principal Financial Officer

Sale15,842$2.50$39.6K
2025-09-02

Sara Kenkare-Mitra

President and Head of R&D

Sale23,638$2.50$59.0K
2025-09-02

Arnon Rosenthal

Chief Executive Officer

Sale51,562$2.50$128.7K
2025-08-26

Paula Hammond

Director

Sale14,000$2.36$33.0K
2025-06-20

Kristine Yaffe

Director

Sale1,000$1.44$1.4K

Source: SEC Form 4 filings. Officers, directors, and 10%+ owners must disclose share transactions within two business days. RSU grants and tax-withholding rows are excluded by default — compensation activity is not a trading signal.

Who owns ALEC

Institutional value

$48.2M

Total shares held

26.5M

Distinct holders

62

-67 vs prior

As of

2026-03-31

Prior: 2025-12-31

Filers with $100M+ AUM disclose holdings 45 days after quarter end.

Top institutional holders

#ManagerSharesValueQoQ changeAction
1BlackRock, Inc.7.7M$16.6M+593.5K (+8.3%)Added
2VANGUARD CAPITAL MANAGEMENT LLC3.7M$7.9MNew
3Merck & Co., Inc.3.5M$7.6M+0 (+0.0%)No change
4VANGUARD PORTFOLIO MANAGEMENT LLC2.6M$5.6MNew
5DEUTSCHE BANK AG\1.1M$2.3M+57.7K (+5.6%)Added
6MACKENZIE FINANCIAL CORP857.4K$1.8M+197.2K (+29.9%)Added
7VANGUARD FIDUCIARY TRUST CO577.9K$1.2MNew
8JANE STREET GROUP, LLC399.5K$858.8K-594.4K (-59.8%)Trimmed
9DIMENSIONAL FUND ADVISORS LP283.8K$609.8K+84.7K (+42.5%)Added
10Invesco Ltd.265.1K$569.9K-14.4K (-5.2%)Trimmed
11Bank of New York Mellon Corp252.3K$542.4K+34.4K (+15.8%)Added
12Nuveen, LLC154.9K$333.1K+21.7K (+16.3%)Added
13UBS Group AG145.3K$312.5K+25.9K (+21.7%)Added
14RHUMBLINE ADVISERS101.3K$217.8K-599 (-0.6%)Trimmed
15STRS OHIO86.5K$186.0K-23.9K (-21.6%)Trimmed
16Jasper Ridge Partners, L.P.73.5K$158.1K-21.5K (-22.7%)Trimmed
17Russell Investments Group, Ltd.66.1K$142.2K-5.8K (-8.0%)Trimmed
18SEI INVESTMENTS CO53.8K$115.8K+37.0K (+218.9%)Added
19HSBC HOLDINGS PLC48.5K$104.8K-48.5K (-50.0%)Trimmed
20JPMORGAN CHASE & CO37.4K$75.5K+4.8K (+14.6%)Added

Source: SEC Form 13F-HR. Positions aggregated across sub-managers within each firm. Options (puts/calls) excluded — common stock only.

Top questions investors are asking

Coming once ALEC's latest filing finishes processing.

Investor sentiment
No votes yet
0 this week · 0 total

Sign in to vote. Votes use 7-day half-life decay.

What matters about ALEC?
Tap any that apply. Aggregates show what other investors flag.

Sign in to tap. 7-day half-life decay.

Latest filing impact
After reading, did this filing make you: