Biological Products, (No Diagnostic Substances) · SIC 2836

Alpha Cognition Inc.

ACOG

Watch

Latest revenue

$3.5M

as of 2026-03-31

Latest net income

$-6.5M

as of 2026-03-31

Net margin

-183.3%

as of 2026-03-31

6.7
of 10

ActaClear Score

Above avg
#61 of 165 in Biological Products, (No Diagnostic Substances)
new
Profitability·25%
7.5
Growth·15%
10.0
Value·20%
5.6
Quality·20%
Momentum·20%
4.5

Computed from 5 years of SEC fundamentals + latest market data, ranked within Biological Products, (No Diagnostic Substances) (165 peers). 10 = best in industry, 5 = median, 0 = worst. Refreshed Jun 6, 2026.

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Price · 5Y

+5.8% / yr 13.9 pts / yr vs S&P 500 8.9% total
Compare:

Live market

delayed ≤15 min
$5.81
0.17%
Market cap
$126.5M
Enterprise value
$74.1M
P/E (trailing)
Forward P/E
P/B
2.20×
Dividend yield
0.0%
52-wk high
$11.54
52-wk low
$4.50
Beta
Shares out
21.8M

5-year trend

What this company does

AI

Alpha Cognition is a biopharma company selling ZUNVEYL, a next-generation acetylcholinesterase inhibitor pill for mild-to-moderate Alzheimer's disease with fewer GI side effects. Revenue comes from U.S. prescription sales targeting nursing homes and long-term care facilities, supplemented by licensing deals like the $44 million CMSI agreement covering Asia, Australia, and New Zealand. The company launched ZUNVEYL on March 19, 2025 and is transitioning from clinical-stage to commercial-stage, targeting operating profitability by 2027 if it shelves pipeline spending.

Generated from ACOG's filing dated 2026-03-31

Key risks

AI
  • Single-product dependence: entire commercial future hinges on ZUNVEYL, launched March 19, 2025, into AChEI market dominated by cheap generics like donepezil.
  • Reimbursement uncertainty: only 2 of 4 major PBMs signed; $820/month WAC faces formulary, prior-auth hurdles against generic AChEIs costing pennies.
  • Cash runway risk: management claims sufficient capital to reach profitability by 2027 only if pipeline development is halted, signaling tight liquidity.

Generated from ACOG's filing dated 2026-03-31

Profitability

Operating margin

-221.7%

97.0%

Net margin

-202.2%

97.8%

Return on equity

-33.1%

110.5%

Return on assets

-25.9%

11.1%

Leverage

Debt / equity

0.28×

102.3%

Debt / assets

21.6%

80.3%

Earnings tracker

QuarterRevenueYoYNet incomeYoYNet margin

Q1 2026

2026-03-31

$3.5M+20.7%$-6.5M-275.5%-183.3%

Q4 2025

2025-12-31

$2.8M$-7.1M-22.8%-255.6%

Q3 2025

2025-09-30

$2.8M$-1.3M+29.1%-46.4%

Q2 2025

2025-06-30

$1.7M$-10.5M-395.8%-632.7%

Q1 2025

2025-03-31

$2.9M$-1.7M+65.5%-58.9%

Q4 2024

2024-12-31

$-5.8M

Q3 2024

2024-09-30

$-1.9M+43.1%

Q2 2024

2024-06-30

$-2.1M+24.9%

Year-over-year change vs the same fiscal quarter one year prior. Revenue + net income sourced from SEC 10-Q / 10-K filings — no analyst-consensus dependency.

Industry trend

Biological Products, (No Diagnostic Substances) · SIC 2836

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Insider activity

Insider buying

$2.9M

Insider selling

$250.0K

Net activity

+$2.6M

Distinct insiders

5

Open-market trades over the last 365 days.

Recent transactions

DateInsiderTypeSharesPriceValue
2026-05-21

Opaleye Management Inc.

10%+ owner

Purchase15,945$5.70$90.9K
2026-05-20

Opaleye Management Inc.

10%+ owner

Purchase8,431$5.89$49.7K
2026-05-19

Lauren D'Angelo

Chief Operating Officer

Purchase3,500$5.76$20.2K
2026-05-18

Opaleye Management Inc.

10%+ owner

Purchase17,395$5.69$99.0K
2026-05-15

Opaleye Management Inc.

10%+ owner

Purchase16,648$5.83$97.0K
2026-03-30

Opaleye Management Inc.

10%+ owner

Purchase1,850$4.99$9.2K
2026-03-27

Opaleye Management Inc.

10%+ owner

Purchase10,000$5.08$50.8K
2026-03-26

Opaleye Management Inc.

10%+ owner

Purchase7,319$5.28$38.7K
2026-03-25

Opaleye Management Inc.

10%+ owner

Purchase8,581$5.43$46.6K
2026-03-24

Opaleye Management Inc.

10%+ owner

Purchase4,182$5.59$23.4K
2026-03-19

Opaleye Management Inc.

10%+ owner

Purchase2,094$5.71$12.0K
2026-03-18

Opaleye Management Inc.

10%+ owner

Purchase2,481$5.75$14.3K
2026-03-16

Opaleye Management Inc.

10%+ owner

Purchase1,331$5.78$7.7K
2026-03-13

Opaleye Management Inc.

10%+ owner

Purchase7,358$5.75$42.3K
2026-03-12

Opaleye Management Inc.

10%+ owner

Purchase5,708$5.85$33.4K
2026-03-09

Opaleye Management Inc.

10%+ owner

Purchase2,179$5.85$12.7K
2026-03-06

Opaleye Management Inc.

10%+ owner

Purchase1,900$5.80$11.0K
2026-03-05

Opaleye Management Inc.

10%+ owner

Purchase42,023$5.80$243.6K
2026-03-05

Opaleye Management Inc.

10%+ owner

Purchase5,000$5.80$29.0K
2026-03-04

Opaleye Management Inc.

10%+ owner

Purchase19,795$5.81$115.0K
2026-03-03

Opaleye Management Inc.

10%+ owner

Purchase46,411$5.75$266.9K
2026-03-03

Opaleye Management Inc.

10%+ owner

Purchase5,000$5.75$28.8K
2026-03-02

Opaleye Management Inc.

10%+ owner

Purchase20,000$5.80$116.0K
2026-02-27

Opaleye Management Inc.

10%+ owner

Purchase3,638$5.99$21.8K
2026-02-26

Opaleye Management Inc.

10%+ owner

Purchase590$5.99$3.5K
2026-02-24

Opaleye Management Inc.

10%+ owner

Purchase53,591$5.80$310.8K
2026-02-24

Opaleye Management Inc.

10%+ owner

Purchase5,000$5.80$29.0K
2026-02-23

Opaleye Management Inc.

10%+ owner

Purchase95,819$5.89$564.6K
2026-02-23

Opaleye Management Inc.

10%+ owner

Purchase4,181$5.89$24.6K
2026-02-20

Opaleye Management Inc.

10%+ owner

Purchase10,000$5.84$58.4K

Source: SEC Form 4 filings. Officers, directors, and 10%+ owners must disclose share transactions within two business days. RSU grants and tax-withholding rows are excluded by default — compensation activity is not a trading signal.

Who owns ACOG

Institutional value

$676.9K

Total shares held

123.3K

Distinct holders

4

-22 vs prior

As of

2026-03-31

Prior: 2025-12-31

Filers with $100M+ AUM disclose holdings 45 days after quarter end.

Top institutional holders

#ManagerSharesValueQoQ changeAction
1VILLERE ST DENIS J & CO LLC71.2K$390.7K-2.7K (-3.7%)Trimmed
2ACT CAPITAL MANAGEMENT, LLC51.5K$282.7K+0 (+0.0%)No change
3UBS Group AG438$2.4K-489 (-52.8%)Trimmed
4Steward Partners Investment Advisory, LLC200$1.1K+0 (+0.0%)No change

Source: SEC Form 13F-HR. Positions aggregated across sub-managers within each firm. Options (puts/calls) excluded — common stock only.

Top questions investors are asking

AI
  1. 1

    With cash runway predicated on no pipeline advancement, what's your current cash balance and quarterly burn post-ZUNVEYL launch?

  2. 2

    Can you quantify ZUNVEYL scripts and net revenue since the March 19 launch, and formulary wins secured to date?

  3. 3

    Given 55% AChEI discontinuation within a year, what's ZUNVEYL's gross-to-net and pricing versus generic donepezil in LTC formularies?

Refreshed when ACOG files a new report · last from 2026-03-31

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